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Article

An investigation of the dihydropyrimidinase-like 2 (DPYSL2) gene in schizophrenia: genetic association study and expression analysis.

The international journal of neuropsychopharmacology - 1 Dec 2006

Zhao Xinzhi, Tang Ruqi, Xiao Zeping, Shi Yongyong, Feng Guoying, Gu Niufan, Shi Jianguo, Xing Yangling, Yan Lijuan, Sang Hong, Zhu Shaomin, Liu Huijun, Chen Wuyan, Liu Jixia, Tang Wei, Zhang Jing, He Lin

Abstract excerpt

Several linkage studies support a susceptibility locus for schizophrenia on chromosome 8p21-22. In this study, we investigated a gene mapping to 8p21, dihydropyrimidinase-like 2 (DPYSL2). DPYSL2 plays an important role in axonal formation and dysfunction of DPYSL2 may result in neurodevelopmental abnormalities. In previous studies, the expression of the gene has been shown to display alteration in the brain of...

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Source

Identifiers

PMID: 16321170
DOI: 10.1017/S1461145705006267

Genes

DPYSL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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