Article
No association between the dihydropyrimidinase-related protein 2 (DRP-2) gene and bipolar disorder in humans.
Neuroscience letters - 9 Oct 2003
Nakata Kenji, Ujike Hiroshi, Tanaka Yuji, Takaki Manabu, Sakai Ayumu, Nomura Akira, Katsu Takeshi, Uchida Naohiko, Imamura Takaki, Fujiwara Yutaka, Hamamura Takashi, Kuroda Shigetoshi
Abstract excerpt
Several susceptibility loci for both of schizophrenia and bipolar disorder (BPD) have been found to overlap on several chromosomes including 8p21. Expression of dihydropyrimidinase-related protein 2 (DRP-2), which gene is located on 8p21, was found to be reduced in the brains of individuals with schizophrenia and BPD. Recently, we demonstrated a significant association between the DRP-2 gene and schizophrenia....
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