Article
Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations.
Translational psychiatry - 7 Aug 2018
Yang Yongfeng, Wang Lu, Li Lingyi, Li Wenqiang, Zhang Yan, Chang Hong, Xiao Xiao, Li Ming, Lv Luxian
Abstract excerpt
Previous genome-wide association studies (GWAS) suggest that rs10489202 in the intron of MPC2 (mitochondrial pyruvate carrier 2) is a risk locus for schizophrenia in Han Chinese populations. To validate this discovery, we conducted a replication analysis in an independent case-control sample of Han Chinese ancestry (437 cases and 2031 controls), followed by a meta-analytic investigation in multiple East Asian...
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