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Article

CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer's disease patients.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Silva Patrícia Natalia, Furuya Tatiane Katsue, Sampaio Braga Ianna, Rasmussen Lucas Trevizani, de Labio Roger Willian, Bertolucci Paulo Henrique, Chen Elizabeth Suchi, Turecki Gustavo, Mechawar Naguib, Payão Spencer Luiz, Mill Jonathan, Smith Marília Cardoso

Abstract excerpt

Alzheimer's disease (AD) is a highly prevalent type of dementia in the elderly population. AD is a complex neurodegenerative disorder. Thus, epigenetic mechanisms that regulate gene expression might have an important role in AD. CNP (2',3'-Cyclic Nucleotide 3' Phosphodiesterase) gene encodes a protein used as an index of myelin alterations. DPYSL2 (Dihydropyrimidinase-like 2) is described as acting in structural...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intercellular Signaling Peptides and Proteins

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 22954668
DOI: 10.3233/JAD-2012-121192

Genes

CNP
DPYSL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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