Article
Population screening for association of mitochondrial haplogroups BM, J, K and M with multiple sclerosis: interrelation between haplogroup J and MS in Persian patients.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Dec 2005
Houshmand M, Sanati M H, Babrzadeh F, Ardalan A, Teimori M, Vakilian M, Akuchekian M, Farhud D, Lotfi J
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is an immunological inflammatory disease of the central nervous system (CNS) which is chronically observed in young adults. On the basis of earlier studies, potential relatedness between MS and mitochondrial DNA (mtDNA) mutations was postulated. MATERIALS AND METHODS: 246 individuals were screened using the PCR-RFLP method, including 70 MS patients examined for mitochondrial...
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