Article
Mitochondrial haplogroups in Basque multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2004
Otaegui D, Sáenz A, Martínez-Zabaleta M, Villoslada P, Fernández-Manchola I, Alvarez de Arcaya A, Emparanza J I, López de Munain A
Abstract excerpt
Previous studies have suggested that mitochondrial metabolism and/or mitochondrial DNA (mtDNA) could be, in conjunction with other genetic or environmental factors, a risk factor for the development of multiple sclerosis (MS). One of these studies establishes that mitochondrial haplogroup JT is a risk factor for developing the disease, in particular the visual manifestations [optic neuritis (ON)]. Nevertheless,...
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