Article
Do mitochondrial DNA haplogroups play a role in susceptibility to tuberculosis?
Respirology (Carlton, Vic.) - 1 Nov 2007
Houshmand Massoud, Banoei Mohammad Mehdi, Tabarsi Payam, Panahi Mehdi Shafa Shariat, Hooshiar Kashani Baharak, Ebrahimi Golnaz, Zargar Laleh, Farnia Parissa, Morris Matthew W, Mansouri Davood, Velayati Ali Akbar, Mirsaeidi Mehdi S
Abstract excerpt
BACKGROUND AND OBJECTIVES: Mitochondrial DNA has a unique role in ATP production and subsequent mitochondrial reactive oxygen species (ROS) production in eukaryotic cells and there is a potential role for ROS and oxygen burst against Mycobacterium tuberculosis, an intracellular pathogen. This study aimed to determine whether the frequency of different mitochondrial haplogroups was significantly different in...
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