Article
mtDNA haplogroup J modulates telomere length and nitric oxide production.
BMC musculoskeletal disorders - 15 Dec 2011
Fernández-Moreno Mercedes, Tamayo María, Soto-Hermida Angel, Mosquera Alejandro, Oreiro Natividad, Fernández-López Carlos, Fernández José Luis, Rego-Pérez Ignacio, Blanco Francisco J
Abstract excerpt
BACKGROUND: Oxidative stress due to the overproduction of nitric oxide (NO) and other oxygen reactive species (ROS), play a main role in the initiation and progression of the OA disease and leads to the degeneration of mitochondria. Therefore, the goal of this work is to describe the difference in telomere length of peripheral blood leukocytes (PBLs) and Nitric Oxide (NO) production between mitochondrial DNA...
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