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Article

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning.

Development (Cambridge, England) - 1 Dec 2005

Ma Lijiang, Lu Mei-Fang, Schwartz Robert J, Martin James F

Abstract excerpt

Cardiac cushion development provides a valuable system to investigate epithelial to mesenchymal transition (EMT), a fundamental process in development and tumor progression. In the atrioventricular (AV) canal, endocardial cells lining the heart respond to a myocardial-derived signal, undergo EMT, and contribute to cushion mesenchyme. Here, we inactivated bone morphogenetic protein 2 (Bmp2) in the AV myocardium of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16314491
DOI: 10.1242/dev.02156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning.PMID 16314491Read ↗

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