Article
Control of endocardial cushion and cardiac valve maturation by BMP signaling pathways.
Molecular genetics and metabolism - 1 Jan 2000
Délot Emmanuèle C
Abstract excerpt
Congenital heart defects, the leading cause of deaths from birth defects, are estimated to occur in close to 1% of live newborns. Among these, abnormal septation of the heart and valve anomalies are the most frequent forms. Despite progress defining several genes involved in normal heart development, we still have a limited understanding of the signaling pathways involved in morphogenesis of the outflow tract...
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