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Article

Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart.

Developmental biology - 15 Jul 2001

Kim R Y, Robertson E J, Solloway M J

Abstract excerpt

The mature heart valves and septa are derived from the cardiac cushions which initially form as local outgrowths of mesenchymal cells within the outflow tract and atrioventricular regions. Endocardial cells respond to signals from the overlying myocardium and undergo an epithelial-to-mesenchymal transformation to invade the intervening extracellular matrix. The molecules that can induce and maintain these cell...

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Identifiers

PMID: 11437450
DOI: 10.1006/dbio.2001.0284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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