Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype.

Inflammatory bowel diseases - 1 Dec 2005

Glas Jürgen, Török Helga-Paula, Tonenchi Laurian, Kapser Julia, Schiemann Uwe, Müller-Myhsok Bertram, Folwaczny Matthias, Folwaczny Christian

Abstract excerpt

UNLABELLED: An increased expression of interleukin-18 (IL-18), a proinflammatory cytokine inducing interferon-gamma, has been found in Crohn's disease (CD). In the IL-18 gene, several partly functional relevant polymorphisms are known. This study sought to investigate associations of IL-18 polymorphisms in inflammatory bowel disease and CD according to CARD15/NOD2 mutation status and clinical phenotypes. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis, Ulcerative
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Interleukin-18

Share to Intracellular Signaling Peptides and Proteins

Share to Linkage Disequilibrium

Share to Nod2 Signaling Adaptor Protein

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 16306764
DOI: 10.1097/01.mib.0000187574.41290.b1

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype.PMID 16306764Read ↗

NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn's disease.Semantic proximity Read ↗

Association of NOD2/CARD15 mutations on Crohn's disease phenotype in an Italian population.Semantic proximity Read ↗

NOD2/CARD15 gene polymorphisms in Crohn's disease: a genotype- phenotype analysis.Semantic proximity Read ↗

NOD2/CARD15 and IL23R genetic variability in 204 Algerian Crohn's disease.Semantic proximity Read ↗

Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study.Semantic proximity Read ↗

Polymorphisms in interleukin-10 gene according to mutations of NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn's disease.Semantic proximity Read ↗

Clinical significance of NOD2/CARD15 and Toll-like receptor 4 gene single nucleotide polymorphisms in inflammatory bowel disease.Semantic proximity Read ↗

NOD2/CARD15 gene polymorphisms in Crohn's disease: a genotype-phenotype analysis in Danish and Portuguese patients and controls.Semantic proximity Read ↗

NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn's disease.Semantic proximity Read ↗

[NOD2/CARD15 mutations and genotype-phenotype correlations in patients with Crohn's disease. Hungarian multicenter study].Semantic proximity Read ↗

NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease.Semantic proximity Read ↗

Crohn's disease is associated with polymorphism of CARD15/NOD2 gene in a Hungarian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.