Article
NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease.
European cytokine network - 1 Jun 2006
Figueroa Carolina, Peralta Alexis, Herrera Luisa, Castro Pedro, Gutiérrez Andrea, Valenzuela Jorge, Aguillón Juan C, Quera Rodrigo, Hermoso Marcela A
Abstract excerpt
Crohn's disease (CD) and ulcerative colitis (UC) are multifactorial diseases with a genetic background. Genes related to the innate immune response have been observed to be involved. Polymorphisms of Toll-like receptor 4 (TLR4) and CARD15/NOD2 are thought to be involved in the pathogenesis of inflammatory bowel disease (IBD). There is no information about the frequency of these polymorphisms in South American and...
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