Article
Crohn's disease is associated with polymorphism of CARD15/NOD2 gene in a Hungarian population.
Annals of the New York Academy of Sciences - 1 Jun 2005
Nagy Zsuzsanna, Karádi Oszkár, Rumi György, Rumi György, Pár Alajos, Mózsik Gyula, Czirják László, Süto Gábor
Abstract excerpt
Crohn's disease (CD) is commonly classified as an immune-mediated disorder, but genetic and environmental factors seem to be important in its pathogenesis. Mutations within the CARD15/NOD2 gene have been associated with CD in the Caucasian population. The aim of our work was to investigate the allele frequency and clinical impact of the three common mutations in Hungarian CD patients and healthy controls....
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