Article
Localization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region.
American journal of human genetics - 1 Mar 1998
Sarfarazi M, Child A, Stoilova D, Brice G, Desai T, Trifan O C, Poinoosawmy D, Crick R P
Abstract excerpt
One of the major causes of blindness is primary open-angle glaucoma, which affects millions of elderly people worldwide. Genetic studies have so far mapped three loci for the adult-onset form of this condition to the 2cen-q13, 3q21-q24, and 8q23 regions. Herein, we report the localization of a fo...
Topics
- Adult
- Age of Onset
- Aged
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Glaucoma, Open-Angle
- Haplotypes
- Humans
- Lod Score
- Male
- Middle Aged
- Phenotype
- Recombination, Genetic