Article
A genome-wide scan maps a novel autosomal dominant juvenile-onset open-angle glaucoma locus to 2p15-16.
Molecular vision - 18 Apr 2008
Lin Ying, Liu Ting, Li Jing, Yang Jiyun, Du Qiong, Wang Junfang, Yang Yang, Liu Xiaoqi, Fan Yuanfu, Lu Fang, Chen Yilian, Pu Yonghong, Zhang Kang, He Xiangge, Yang Zhenglin
Abstract excerpt
PURPOSE: To study the clinical features and to perform genetic linkage study in two large Chinese families with autosomal dominant juvenile-onset primary open-angle glaucoma (POAG). METHODS: Eighteen members of one Chinese family and 25 members of a second Chinese family with juvenile-onset primary open-angle glaucoma (POAG) were investigated. Thirteen members in one family and 14 members in the second family...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Aged, 80 and over
- China
- Chromosomes, Human, Pair 2
- DNA Mutational Analysis
- Female
- Fundus Oculi
- Genes, Dominant