Article
Genome-wide scan for adult onset primary open angle glaucoma.
Human molecular genetics - 12 Apr 2000
Wiggs J L, Allingham R R, Hossain A, Kern J, Auguste J, DelBono E A, Broomer B, Graham F L, Hauser M, Pericak-Vance M, Haines J L
Abstract excerpt
Adult onset primary open angle glaucoma is a leading cause of blindness throughout the world. The disease results in an apoptotic death of retinal ganglion cells that is usually associated with an elevation of intraocular pressure. Familial aggregation of the disorder provides evidence for strong genetic influences that are likely to be the result of multiple susceptibility genes. A two-stage genome scan to...
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