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Article

Peroxisome proliferator-activated receptor alpha L162V polymorphism in nonalcoholic steatohepatitis and genotype 1 hepatitis C virus-related liver steatosis.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Nov 2005

Verdi Hasibe, Koytak Elif Sare, Onder Oğuz, Ergül Ayça Arslan, Cinar Kubilay, Idilman Ramazan, Erden Esra, Bozdayi Abdurrahman Mithat, Yurdaydin Cihan, Uzunalimoglu Ozden, Bozkaya Hakan

Abstract excerpt

BACKGROUND: Peroxisome proliferator-activated receptor alpha (PPARalpha) plays important roles in lipid metabolism. A recently discovered L162V polymorphism of the PPARalpha gene is associated with enhanced transcriptional activity. In this study, the frequency of L162V was investigated in nonalcoholic steatohepatitis (NASH) and genotype 1 hepatitis C virus (HCV)-related liver steatosis. METHODS: Seventy-two NASH...

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Source

Identifiers

PMID: 16297361
DOI: 10.2310/6650.2005.53706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Peroxisome proliferator-activated receptor alpha L162V polymorphism in nonalcoholic steatohepatitis and genotype 1 hepatitis C virus-related liver steatosis.PMID 16297361Read ↗

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PPAR-alpha L162V and PGC-1 G482S gene polymorphisms, but not PPAR-gamma P12A, are associated with alcohol consumption in a Spanish Mediterranean population.Semantic proximity Read ↗

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