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Article

PPAR-alpha L162V and PGC-1 G482S gene polymorphisms, but not PPAR-gamma P12A, are associated with alcohol consumption in a Spanish Mediterranean population.

Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2008

Francès F, Verdú F, Portolés O, Castelló A, Sorlí J V, Guillen M, Corella D

Abstract excerpt

BACKGROUND: Peroxisome Proliferator-Activated Receptors (PPARs) and its co-activators are regulatory elements of the cellular lipid homeostasis and have been associated with feeding behavior modulation. Animal models suggest that these genes may be involved in alcohol consumption regulation. However, no studies in humans exist. Our aim is to estimate the possible association between polymorphisms in the...

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Source

Identifiers

PMID: 18786524
DOI: 10.1016/j.cca.2008.08.011

Genes

PGC

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PPAR-alpha L162V and PGC-1 G482S gene polymorphisms, but not PPAR-gamma P12A, are associated with alcohol consumption in a Spanish Mediterranean population.PMID 18786524Read ↗

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