Article
Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD).
BMC gastroenterology - 27 Jun 2008
Yoneda Masato, Hotta Kikuko, Nozaki Yuichi, Endo Hiroki, Uchiyama Takashi, Mawatari Hironori, Iida Hiroshi, Kato Shingo, Hosono Kunihiro, Fujita Koji, Yoneda Kyoko, Takahashi Hirokazu, Kirikoshi Hiroyuki, Kobayashi Noritoshi, Inamori Masahiko, Abe Yasunobu, Kubota Kensuke, Saito Satoru, Maeyama Shiro, Wada Koichiro, Nakajima Atsushi
Abstract excerpt
BACKGROUND: Genetic factors as well as environmental factors are important in the development of NAFLD and in this study we investigated associations between polymorphisms of peroxisome proliferators-activated receptor gamma coactivator 1alpha polymorphism (PPARGC1A) and NAFLD. AIMS: We recruited 115 patients with biopsy-proven NAFLD, 65 with NASH and 50 with simple steatosis, and 441 healthy control subjects and...
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