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Article

The C-681G polymorphism of the PPAR-γ gene is associated with susceptibility to non-alcoholic fatty liver disease.

The Tohoku journal of experimental medicine - 1 Aug 2012

Cao Chuang-Yu, Li Yu-Yuan, Zhou Yong-Jian, Nie Yu-Qiang, Wan Yu-Jui Yvonne

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is defined as excessive accumulation of fatty acid in the liver, a common disease in the world. The research of single nucleotide polymorphisms (SNPs) provides a new approach for managing NAFLD. SNPs may increase or decrease the functions of the target genes and their encoding proteins. Peroxisome proliferator-activated receptor (PPAR) plays a key role in modulating...

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Identifiers

PMID: 22820754
DOI: 10.1620/tjem.227.253
PMCID: PMC4126502

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