Article
Multiple synergizing factors contribute to the strength of the CD8+ T cell response against listeriolysin O.
International immunology - 1 Jan 2006
Bruder Dunja, Nussbaum Alexander K, Gakamsky Dimitry M, Schirle Markus, Stevanovic Stefan, Singh-Jasuja Harpreet, Darji Ayub, Chakraborty Trinad, Schild Hansjörg, Pecht Israel, Weiss Siegfried
Abstract excerpt
Immunodominance in CD8+ T cell responses against Listeria monocytogenes is a well-recognized but still not fully understood phenomenon. From listeriolysin, the major virulence factor of L. monocytogenes, only a single epitope, pLLO91-99, is presented by MHC class I molecules in BALB/c mice which dominates the cytotoxic T cell response against this bacterial pathogen. To obtain more insights into the molecular and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
