Article
Parameters that influence the efficiency of processing antigenic epitopes expressed in Salmonella typhimurium.
Infection and immunity - 1 Oct 1994
Wick M J, Harding C V, Normark S J, Pfeifer J D
Abstract excerpt
We investigated parameters that affect the efficiency with which antigenic epitopes from Salmonella typhimurium are processed for presentation to T lymphocytes. As a model system, the hen egg white lysozyme 52-61 [HEL(52-61)] epitope, which binds the murine major histocompatibility complex class II (MHC-II) molecule I-Ak, was expressed in soluble fusion proteins in S. typhimurium. Murine peritoneal macrophages...
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