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Article

HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis.

Developmental cell - 1 Feb 2008

Goodyer William, Kaitna Susanne, Couteau Florence, Ward Jordan D, Boulton Simon J, Zetka Monique

Abstract excerpt

Repair of the programmed meiotic double-strand breaks (DSBs) that initiate recombination must be coordinated with homolog pairing to generate crossovers capable of directing chromosome segregation. Chromosome pairing and synapsis proceed independently of recombination in worms and flies, suggesting a paradoxical lack of coregulation. Here, we find that the meiotic axis component HTP-3 links DSB formation with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18267094
DOI: 10.1016/j.devcel.2007.11.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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