Article
Evolution of myelin proteolipid proteins: gene duplication in teleosts and expression pattern divergence.
Molecular and cellular neurosciences - 1 Jan 2006
Schweitzer Jörn, Becker Thomas, Schachner Melitta, Nave Klaus-Armin, Werner Hauke
Abstract excerpt
The coevolution of neurons and their supporting glia to the highly specialized axon-myelin unit included the recruitment of proteolipids as neuronal glycoproteins (DMbeta, DMgamma) or myelin proteins (DMalpha/PLP/DM20). Consistent with a genome duplication at the root of teleosts, we identified three proteolipid pairs in zebrafish, termed DMalpha1 and DMalpha2, DMbeta1 and DMbeta2, DMgamma1 and DMgamma2. The...
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