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Article

IL6, IL10 and TGFB1 gene polymorphisms in coeliac disease: differences between DQ2 positive and negative patients.

Allergologia et immunopathologia - 1 Jan 2000

Garrote J A, Arranz E, Gómez-González E, León A J, Farré C, Calvo C, Bernardo D, Fernández-Salazar L, Blanco-Quirós A

Abstract excerpt

UNLABELLED: Predisposition to coeliac disease (CD) might be partially due to an individual pattern of hyper-inflammatory biased immune response. One of these patterns of intense response may be linked to the haplotype carrying HLA-DQ2 alleles and TNF -308A allele. However, 10 % of CD patients do not express the DQ2 heterodimer and these do not usually carry the TNF -308A allele. A similar response might be...

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Source

Identifiers

PMID: 16287542
DOI: 10.1157/13080926

Genes

TNF
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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