Article
TNF alpha and LT alpha gene polymorphisms as additional markers of celiac disease susceptibility in a DQ2-positive population.
Immunogenetics - 1 Nov 2002
Garrote José A, Arranz Eduardo, Tellería Juan J, Castro Jesús, Calvo Carmen, Blanco-Quirós Alfredo
Abstract excerpt
TNFalpha and TNFbeta, or linfotoxin (LTalpha), are two molecules playing an important role in inflammation. Their genes map on Chromosome 6, between the HLA class II and class I loci. Polymorphisms in, or near, TNF genes have been associated with susceptibility to several autoimmune diseases. Stu...
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