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Article

IL10 promoter haplotypes may contribute to altered cytokine expression and systemic inflammation in celiac disease.

Clinical immunology (Orlando, Fla.) - 1 May 2018

Hofmann S R, Laass M W, Fehrs A, Schuppan D, Zevallos V F, Salminger D, Mäbert K, Hedrich C M

Abstract excerpt

Celiac disease (CD) is an autoimmune/inflammatory condition triggered by dietary gluten intake in genetically predisposed individuals. Though associations with MHC class II HLA-DQ2 or -DQ8 are the primary and necessary genetic predisposition for CD, >97% of genetically predisposed individuals never develop CD. Cytokines were measured in the serum of CD patients and controls. Possible associations with IL10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29481982
DOI: 10.1016/j.clim.2018.02.010

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