Article
Cytokine gene polymorphisms and genetic association with coeliac disease in the Finnish population.
Scandinavian journal of immunology - 1 Jan 2005
Woolley N, Mustalahti K, Mäki M, Partanen J
Abstract excerpt
Coeliac disease (CD) is an intestinal disorder caused by intolerance to dietary gluten in susceptible individuals. The HLA-DQ genes are major risk factors for CD, but other genes also play an important role in the disease susceptibility. Immune-mediated mechanisms are known to underlie the pathogenesis of CD. We studied single-nucleotide polymorphisms in transforming growth factor (TGF)-beta1, interleukin...
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