Article
Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.
Molecular and cellular biology - 1 Jan 2013
Tomson Brett N, Crisucci Elia M, Heisler Lawrence E, Gebbia Marinella, Nislow Corey, Arndt Karen M
Abstract excerpt
Across diverse eukaryotes, the Paf1 complex (Paf1C) plays critical roles in RNA polymerase II transcription elongation and regulation of histone modifications. Beyond these roles, the human and Saccharomyces cerevisiae Paf1 complexes also interact with RNA 3'-end processing components to affect transcript 3'-end formation. Specifically, the Saccharomyces cerevisiae Paf1C functions with the RNA binding proteins...
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