Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SAGA and Rpd3 chromatin modification complexes dynamically regulate heat shock gene structure and expression.

The Journal of biological chemistry - 20 Nov 2009

Kremer Selena B, Gross David S

Abstract excerpt

The chromatin structure of heat shock protein (HSP)-encoding genes undergoes dramatic alterations upon transcriptional induction, including, in extreme cases, domain-wide nucleosome disassembly. Here, we use a combination of gene knock-out, in situ mutagenesis, chromatin immunoprecipitation, and expression assays to investigate the role of histone modification complexes in regulating heat shock gene structure and...

Topics

Animals
Chromatin
Chromatin Immunoprecipitation
HSP90 Heat-Shock Proteins
Heat-Shock Proteins
Histone Acetyltransferases
Histone Deacetylases
Humans
Mutagenesis
Mutation
Nucleosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 19759026
DOI: 10.1074/jbc.M109.058610
PMCID: PMC2781707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SAGA and Rpd3 chromatin modification complexes dynamically regulate heat shock gene structure and expression.PMID 19759026Read ↗

Multi-tasking on chromatin with the SAGA coactivator complexes.Semantic proximity Read ↗

Modular Architecture of the SAGA Complex Governs Stress Adaptation, Morphogenesis, and Histone Acetylation in <i>Candida albicans</i>Semantic proximity Read ↗

The TAF9 C-terminal conserved region domain is required for SAGA and TFIID promoter occupancy to promote transcriptional activation.Semantic proximity Read ↗

TFIID and Spt-Ada-Gcn5-acetyltransferase functions probed by genome-wide synthetic genetic array analysis using a Saccharomyces cerevisiae taf9-ts allele.Semantic proximity Read ↗

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.Semantic proximity Read ↗

SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin.Semantic proximity Read ↗

Genome-wide localization analysis of a complete set of Tafs reveals a specific effect of the taf1 mutation on Taf2 occupancy and provides indirect evidence for different TFIID conformations at different promoters.Semantic proximity Read ↗

Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction.Semantic proximity Read ↗

ASF1 and the SWI/SNF complex interact functionally during nucleosome displacement, while FACT is required for nucleosome reassembly at yeast heat shock gene promoters during sustained stress.Semantic proximity Read ↗

A critical role for heat shock transcription factor in establishing a nucleosome-free region over the TATA-initiation site of the yeast HSP82 heat shock gene.Semantic proximity Read ↗

Distinct mutations in yeast TAF(II)25 differentially affect the composition of TFIID and SAGA complexes as well as global gene expression patterns.Semantic proximity Read ↗

Genome-wide, time-sensitive interrogation of the heat shock response under diverse stressors via ReporterSeqSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.