Article
Effective algorithms for tag SNP selection.
Journal of bioinformatics and computational biology - 1 Oct 2005
Liu Tie-Fei, Sung Wing-Kin, Li Yi, Liu Jian-Jun, Mittal Ankush, Mao Pei-Lin
Abstract excerpt
Single nucleotide polymorphisms (SNPs), due to their abundance and low mutation rate, are very useful genetic markers for genetic association studies. However, the current genotyping technology cannot afford to genotype all common SNPs in all the genes. By making use of linkage disequilibrium, we can reduce the experiment cost by genotyping a subset of SNPs, called Tag SNPs, which have a strong association with...
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