Article
Tag SNP selection via a genetic algorithm.
Journal of biomedical informatics - 1 Oct 2010
Mahdevar Ghasem, Zahiri Javad, Sadeghi Mehdi, Nowzari-Dalini Abbas, Ahrabian Hayedeh
Abstract excerpt
Single Nucleotide Polymorphisms (SNPs) provide valuable information on human evolutionary history and may lead us to identify genetic variants responsible for human complex diseases. Unfortunately, molecular haplotyping methods are costly, laborious, and time consuming; therefore, algorithms for constructing full haplotype patterns from small available data through computational methods, Tag SNP selection...
Topics
- Algorithms
- Computational Biology
- Computer Simulation
- Disease
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Models, Genetic
- Polymorphism, Single Nucleotide
- Software
