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Article

CGTS: a site-clustering graph based tagSNP selection algorithm in genotype data.

BMC bioinformatics - 30 Jan 2009

Wang Jun, Guo Mao-zu, Wang Chun-yu

Abstract excerpt

BACKGROUND: Recent studies have shown genetic variation is the basis of the genome-wide disease association research. However, due to the high cost on genotyping large number of single nucleotide polymorphisms (SNPs), it is essential to choose a small subset of informative SNPs (tagSNPs), which are able to capture most variation in a population, to represent the rest SNPs. Several methods have been proposed to...

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PMID: 19208176
DOI: 10.1186/1471-2105-10-S1-S71
PMCID: PMC2648800

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