Article
APOE ε4 and the risk for Alzheimer disease and cognitive decline in African Americans and Yoruba.
International psychogeriatrics - 1 Jun 2014
Hendrie Hugh C, Murrell Jill, Baiyewu Olusegun, Lane Kathleen A, Purnell Christianna, Ogunniyi Adesola, Unverzagt Frederick W, Hall Kathleen, Callahan Christopher M, Saykin Andrew J, Gureje Oye, Hake Ann, Foroud Tatiana, Gao Sujuan
Abstract excerpt
BACKGROUND: There is little information on the association of the APOEe4 allele and AD risk in African populations. In previous analyses from the Indianapolis-Ibadan dementia project, we have reported that APOE ε4 increased the risk for Alzheimer's disease (AD) in African Americans but not in Yoruba. This study represents a replication of this earlier work using enriched cohorts and extending the analysis to...
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