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Article

Codon usage bias from tRNA's point of view: redundancy, specialization, and efficient decoding for translation optimization.

Genome research - 1 Nov 2004

Rocha Eduardo P C

Abstract excerpt

The selection-mutation-drift theory of codon usage plays a major role in the theory of molecular evolution by explaining the co-evolution of codon usage bias and tRNA content in the framework of translation optimization. Because most studies have focused only on codon usage, we analyzed the tRNA gene pool of 102 bacterial species. We show that as minimal generation times get shorter, the genomes contain more tRNA...

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Identifiers

PMID: 15479947
DOI: 10.1101/gr.2896904
PMCID: PMC525687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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