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Article

Analysis of genetic variations in the exon 27 region of the canine BRCA2 locus.

The Journal of veterinary medical science - 1 Oct 2005

Yoshikawa Yasunaga, Morimatsu Masami, Ochiai Kazuhiko, Nagano Masashi, Yamane Yoshihisa, Tomizawa Nobuyuki, Sasaki Nobuo, Hashizume Kazuyoshi

Abstract excerpt

Mammary tumors are the most common tumor type in women as well as in female dogs. The BRCA2 gene encodes a large nuclear protein that is involved in DNA repair, and mutations in the human BRCA2 confer an increased risk of female mammary tumors. The BRCA2 protein acts as a tumor suppressor, and inactivation of BRCA2 by loss of heterozygosity is implicated in mammary carcinogenesis. In this study, to establish an...

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Source

Identifiers

PMID: 16276057
DOI: 10.1292/jvms.67.1013

Genes

BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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