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Article

Novel variations and loss of heterozygosity of BRCA2 identified in a dog with mammary tumors.

American journal of veterinary research - 1 Oct 2008

Yoshikawa Yasunaga, Morimatsu Masami, Ochiai Kazuhiko, Nagano Masashi, Tomioka Yukiko, Sasaki Nobuo, Hashizume Kazuyoshi, Iwanaga Toshihiko

Abstract excerpt

OBJECTIVE: To establish novel polymorphic markers for analysis of loss of heterozygosity (LOH), so as to study the possible involvement of BRCA2 in mammary tumors obtained from dogs. SAMPLE POPULATION: Blood samples, mammary gland specimens, or mammary tumors from 3 tumor-bearing dogs and 10 tumor-free dogs. PROCEDURES: Nucleotide sequence analysis was performed with a DNA autosequencer. Loss of heterozygosity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18828690
DOI: 10.2460/ajvr.69.10.1323

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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