Article
Liquid biopsy can detect BRCA2 gene variants in female dogs with mammary neoplasia.
Veterinary and comparative oncology - 1 Mar 2022
de Oliveira Jéssica Rodrigues, Colombo Jucimara, Gonçalves Francine Moraes, de Carvalho Lucas Amoroso Lopes, Costa Douglas Santos, Henrique Tiago, Novais Adriana Alonso, Moschetta-Pinheiro Marina Gobbe, Chuffa Luiz Gustavo de Almeida, Coutinho Luiz Lehmann, Santana Áureo Evangelista, Zuccari Debora Aparecida Pires de Campos
Abstract excerpt
Mammary tumours (MT) are one of the most prevalent malignancies in female dogs and women. Currently, molecular analyzes have shown that each tumour type presents its own genetic signature. In this context, liquid biopsy allows a comprehensive genetic characterisation of the tumour, enabling early diagnosis and personalised treatment of patients. In women, deleterious mutations inherited in BRCA2 gene are...
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