Article
Molecular evidence for arterial repair in atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America - 15 Nov 2005
Karra Ravi, Vemullapalli Sreekanth, Dong Chunming, Herderick Edward E, Song Xiaohua, Slosek Kathy, Nevins Joseph R, West Mike, Goldschmidt-Clermont Pascal J, Seo David
Abstract excerpt
Atherosclerosis is a chronic inflammatory process and progresses through characteristic morphologic stages. We have shown previously that chronically injecting bone-marrow-derived vascular progenitor cells can effect arterial repair. This repair capacity depends on the age of the injected marrow cells, suggesting a progressive decline in progenitor cell function. We hypothesized that the progression of...
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