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Transcriptome analysis of mouse aortae reveals multiple novel pathways regulated by aging

15 Aug 2020

Abstract excerpt

Vascular aging has been documented as a vital process leading to arterial dysfunction and age-related cardiovascular and cerebrovascular diseases. However, our understanding of the molecular underpinnings of age-related phenotypes in the vascular system is incomplete. Here we performed bulk RNA sequencing in young and old mouse aortae to elucidate age-associated changes in the transcriptome. Results showed that...

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PMID: 32805724
DOI: 10.18632/aging.103652

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