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Endothelial Injury and Repair: A Novel Theory for Atherosclerosis

27 May 2008

Abstract excerpt

The traditional view of atherosclerosis as a pathological lipid deposition within the artery wall has been redefined by a more complex theory in which the presence of a dysfunctional endothelium plays a pivotal role. The discovery of progenitor cells of myeloid origin, which are able to replace old or injured mature endothelial cells and are able to differentiate into healthy and functional endothelial cells, has...

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PMID: 18628277
DOI: 10.1177/0003319708320761

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