Article
The human placental derived BeWo cell line: a useful model for selecting Plasmodium falciparum CSA-binding parasites.
Experimental parasitology - 1 Feb 2006
Viebig Nicola K, Nunes Marta C, Scherf Artur, Gamain Benoit
Abstract excerpt
Chondroitin sulfate A (CSA) present in the placental intervillous blood spaces has been described as the main receptor involved in the massive sequestration of Plasmodium falciparum parasitized erythrocytes to the placenta. Placental parasite isolates are functionally distinct from isolates that sequester in other organs, because they do not cytoadhere to CD36 but instead bind to CSA. To investigate for the...
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