Article
Chondroitin-4-sulfate impairs in vitro and in vivo cytoadherence of Plasmodium falciparum infected erythrocytes.
Molecular medicine (Cambridge, Mass.) - 1 Aug 1997
Pouvelle B, Meyer P, Robert C, Bardel L, Gysin J
Abstract excerpt
BACKGROUND: Chondroitin-4-sulfate (CSA) was recently described as a Plasmodium falciparum cytoadherence receptor present on Saimiri brain microvascular and human lung endothelial cells. MATERIALS AND METHODS: To specifically study chondroitin-4-sulfate-mediated cytoadherence, a parasite populatio...
Topics
- Animals
- Cell Adhesion
- Cell Line
- Chondroitin Sulfates
- Endothelium, Vascular
- Erythrocytes
- Female
- Hyaluronan Receptors
- Malaria, Falciparum
- Male
- Phenotype
- Plasmodium falciparum
- Saimiri
- Thrombomodulin