Article
Chondroitin sulfate proteoglycan but not hyaluronic acid is the receptor for the adherence of Plasmodium falciparum-infected erythrocytes in human placenta, and infected red blood cell adherence up-regulates the receptor expression.
The American journal of pathology - 1 Jun 2007
Muthusamy Arivalagan, Achur Rajeshwara N, Valiyaveettil Manojkumar, Botti John J, Taylor Diane W, Leke Rose F, Gowda D Channe
Abstract excerpt
A low-sulfated chondroitin sulfate proteoglycan (CSPG) has been shown to be the receptor for the adherence of Plasmodium falciparum-infected red blood cells (IRBCs) in human placenta. Recently, hyaluronic acid (HA) has been suggested as an additional receptor even though IRBC binding to HA and the presence of HA at locations where IRBCs adhere in the placenta have not been established. In this study, we...
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