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Article

A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A.

EMBO reports - 1 Aug 2005

Viebig Nicola K, Gamain Benoit, Scheidig Christine, Lépolard Catherine, Przyborski Jude, Lanzer Michael, Gysin Jürg, Scherf Artur

Abstract excerpt

In high-transmission regions, protective clinical immunity to Plasmodium falciparum develops during the early years of life, limiting serious complications of malaria in young children. Pregnant women are an exception and are especially susceptible to severe P. falciparum infections resulting from the massive adhesion of parasitized erythrocytes to chondroitin sulphate A (CSA) present on placental...

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Source

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Identifiers

PMID: 16025132
DOI: 10.1038/sj.embor.7400466
PMCID: PMC1369142

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Source receipt: pubmed, retrieved 7 Sept 2026.

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A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A.PMID 16025132Read ↗

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Evidence for the Involvement of VAR2CSA in Pregnancy-associated MalariaSemantic proximity Read ↗

Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites.Semantic proximity Read ↗

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