Article
Molecular characterization of isoniazid resistance in Mycobacterium tuberculosis: identification of a novel mutation in inhA.
Antimicrobial agents and chemotherapy - 1 Mar 2006
Leung E T Y, Ho P L, Yuen K Y, Woo W L, Lam T H, Kao R Y, Seto W H, Yam W C
Abstract excerpt
Multiplex allele-specific PCRs detecting katG codon 315 and mabA (bp -15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr was characterized to show strong association with isoniazid resistance in Mycobacterium tuberculosis.
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