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Article

Requirement of DNA polymerase eta for error-free bypass of UV-induced CC and TC photoproducts.

Molecular and cellular biology - 1 Jan 2001

Yu S L, Johnson R E, Prakash S, Prakash L

Abstract excerpt

The yeast RAD30-encoded DNA polymerase eta (Poleta) bypasses a cis-syn thymine-thymine dimer efficiently and accurately. Human DNA polymerase eta functions similarly in the bypass of this lesion, and mutations in human Poleta result in the cancer prone syndrome, the variant form of xeroderma pigmentosum. UV light, however, also elicits the formation of cis-syn cyclobutane dimers and (6-4) photoproducts at...

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Identifiers

PMID: 11113193
DOI: 10.1128/MCB.21.1.185-188.2001
PMCID: PMC88792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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