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Article

Cytoplasmic transport signal is involved in phogrin targeting and localization to secretory granules.

Traffic (Copenhagen, Denmark) - 1 Dec 2005

Torii Seiji, Saito Naoya, Kawano Ayumi, Zhao Shengli, Izumi Tetsuro, Takeuchi Toshiyuki

Abstract excerpt

Phogrin is an integral glycoprotein primarily expressed in neuroendocrine cells. The predominant localization of phogrin is on dense-core secretory granules, and the lumenal domain has been shown to be involved in its efficient sorting to the regulated secretory pathway. Here, we present data showing that a leucine-based sorting signal [EExxxIL] within the cytoplasmic tail contributes its steady-state...

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PMID: 16262730
DOI: 10.1111/j.1600-0854.2005.00353.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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