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Article

Secretory granule biogenesis and neuropeptide sorting to the regulated secretory pathway in neuroendocrine cells.

Journal of molecular neuroscience : MN - 1 Jan 2004

Loh Y Peng, Kim Taeyoon, Rodriguez Yazmin M, Cawley Niamh X

Abstract excerpt

Neuropeptide precursors synthesized at the rough endoplasmic reticulum are transported and sorted at the trans-Golgi network (TGN) to the granules of the regulated secretory pathway (RSP) of neuroendocrine cells. They are then processed into active peptides and stored in large dense-core granules (LDCGs) until secreted upon stimulation. We have studied the regulation of biogenesis of the LDCGs and the mechanism...

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Source

Identifiers

PMID: 14742911
DOI: 10.1385/JMN:22:1-2:63

Genes

POMC
CPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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